Figure 1
Anesthesia protocol results in sustainable physiology. (a) Timeline of anesthesia induction and experiment using dexmedetomidine/isoflurane (left) and ketamine/xylazine (right). (b) Arterial blood gas (ABG) measurements carried out 1, 2, 4, 6, and 8 h post induction shown as mean ± SEM (n = 5 mice per anesthetic). Each open circle represents the individual animal value. One-way ANOVA measures for (K/X;D/I): pO2 (P = 0.92;0.52), pCO2 (P = 0.83;0.65), pH (P = 0.17;0.98). (c) Heart rate and respiration rate recorded at 30 min intervals during ABG measurement. Data are represented as mean ± SEM.
