Figure 2
Individual mouse BOLD fMRI temporal sensitivity obtained under D/I and K/X anesthesia. (a) ROI definitions overlaid onto mean EPI images. CPu, caudate putamen; M1, primary motor cortex; M2, secondary motor cortex; POm, posterior medial thalamus; S1BC, primary somatosensory barrel cortex; S1FL, primary somatosensory forelimb; SC, superior colliculus; VP, ventral posterior nucleus. Coordinates below refer to distance to bregma (mm). (B-C) Response map from simultaneous FP and WP stimulation from an individual mouse under D/I (b) and K/X (c) anesthesia at 2 h and 4 h post-induction. P < 0.005 uncorrected. (d) Percent change plotted at post-2 h and post-4 h induction. Gray shaded areas indicate stimulation period. Left hemisphere ROIs were used for S1BC, S2, and POm, whereas S1FL is from the right hemisphere.
