Figure 3
Temporal sensitivity and stability of mouse BOLD fMRI under D/I and K/X anesthesia. (a) Cropped group activation map showing S1BC and S2 ROIs (rostral slice) and S1BC, S2, and thalamic ROIs (caudal slice in cyan) over time under both anesthesia conditions from simultaneous FP and WP stimulation. Cluster-wise FWE corrected P = 0.05. r, rostral; c, caudal. (b) Mean t-values extracted from respective ROIs plotted over time as mean ± SD under D/I (blue) and K/X (red). Individual mouse values are plotted as different symbols (n = 6). (c) Temporal stability calculated by the average of t-values across time divided by SD for each mouse is plotted as mean ± SEM from each ROI. Dots represent individual mouse values (n = 6 for each anesthetic). Corrected two-sample unpaired t-test, *P < 0.05, **P < 0.01, ***P < 0.001.
