Figure 4 | Scientific Reports

Figure 4

From: Identification of biological pathway and process regulators using sparse partial least squares and triple-gene mutual interaction

Figure 4

Regulatory network generated by triple-gene mutual interaction (TGMI) (A) and sparse partial least squares (SPLS) (B) for the Populus trichocarpa lignin biosynthesis pathway using the RNA-seq data generated from developing xylem tissues. The green nodes represent pathway genes. All other nodes are the top 50 transcription factors that have the highest connectivity to pathway genes regardless of their colors. The light coral nodes represent positive known TFs of lignin biosynthesis while the red edges are to show the connections of a true positive known pathway regulator with pathway genes.

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