Table 1 The patients’ characteristics.

From: Interactions of nasal epithelium with macrophages and dendritic cells variously alter urban PM-induced inflammation in healthy, asthma and COPD

 

Control n = 8

Asthma n = 10

COPD n = 8

Overall p valuea

Pairwise p value*

Asthma versus control

COPD versus control

Asthma versus COPD

Age (years)

38.5 (32.5–48)

55 (38–62)

62 (59.5–72.5)

0.005

0.138

0.0002

0.138

Gender (F/M)

6/2

3/10

5/3

0.046

BMI (kg/m2)

22.1 (20.7–24.1)

26.9 (26–27.7)

28 (25.4–30.3)

0.002

0.002

0.0003

0.696

Atopy (n)

3

8

2

0.03

Smoking exposure (pack-years)

0 (0–0)

0 (0–4)

32.5 (22.5–50)

0.0002

0.277

0.0002

0.0003

FEV1 (% predicted)

103 (81–111)

81 (75–94)

61.5 (51.5–76.5)

0.006

0.043

0.004

0.034

FEV1/VC (%)

106 (81.8–112)

82 (75–86)

54 (50–68)

0.0003

0.02

0.0006

0.0004

FeNO (ppb)

11.0 (9.3–12.6)

52.3 (31.3–77.6)

17.4 (12.6–26.1)

0.0047

0.03

0.333

0.003

ACT (points)

N.A

20.5 (17–25)

N.A

N.A

N.A

N.A

N.A

ICS treatment (n)

N.A

6

1

N.A

N.A

N.A

N.A

CAT (points)

N.A

N.A

10.5 (8–15)

N.A

N.A

N.A

N.A

mMRC (points)

N.A

N.A

1.5 (1–3)

N.A

N.A

N.A

N.A

  1. Data are presented as median (IQR) or n.
  2. ACT Asthma control test, BMI body mass index, FeNO fractional exhaled nitric oxide FEV1 forced expiratory volume at first second, ICS inhaled corticosteroids, mMRC modified Medical Research Council, N.A. not applicable, VC vital capacity.
  3. aKruskal Wallis or Chi square test, *Mann–Whitney U test.
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