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Figure 3

From: Quantitative not qualitative histology differentiates aneurysmal from nondilated ascending aortas and reveals a net gain of medial components

Figure 3

Correlation of histology data. Nondilated ascending aortas from organ donors and aneurysmal ascending aortas from patients undergoing surgical repair were analyzed by histopathology and histomorphometry. Association of medial degeneration score and (A) media thickness, (B) medial fraction of elastin by Verhoeff stain, and (C) number of SMC per cross-section (x-sec). (D) Matrix of correlation coefficients among quantitative data. Correlation of (E) medial fraction of elastin to cytoplasm by Movat stain, (F) medial fraction of elastin by Verhoeff stain to number of SMC per cross-sectional area, (G) number of SMC per cross-sectional area to aorta diameter, (H) number of SMC per cross-sectional area to media cross-sectional area, and (I) medial fraction of collagen by Movat stain to adventitia thickness. Individual data shown with bars representing mean ± SD, n = 17 nondilated and n = 18 aneurysms, and comparisons were by Kruskal–Wallis test with Dunn’s multiple comparisons test (A–C) or by Spearman correlation (D–I).

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