Table 1 Subject characteristics.

From: Quantitative not qualitative histology differentiates aneurysmal from nondilated ascending aortas and reveals a net gain of medial components

 

Nondilated

Aneurysm

P value

n = 17

n = 18

Age (years)

48.6 ± 18.4

62.7 ± 11.0

0.0273

Sex (male)

11 (65%)

16 (89%)

0.1212

Race

     African American

4 (24%)

0 (0%)

0.0299

     Caucasian

9 (53%)

16 (89%)

     Hispanic

4 (24%)

2 (11%)

Body surface area (m2)

1.98 ± 0.24

2.06 ± 0.29

0.2584

Aorta diameter (cm)

3.18 ± 0.40

5.19 ± 0.46

< 0.0001

Aorta z-score

− 0.25 ± 1.04

5.56 ± 1.77

< 0.0001

Bicuspid aortic valve

1 (6%)

9 (50%)

0.0072

Aortic valve insufficiency

0 (0%)

11 (61%)

0.0001

Aortic valve stenosis

1 (6%)

4 (22%)

0.3377

Aortic atherosclerosis

5 (29%)

1 (6%)

0.0877

Hypertension

6 (35%)

12 (67%)

0.0943

Hyperlipidemia

2 (12%)

12 (67%)

0.0016

Diabetes mellitus

2 (12%)

3 (17%)

> 0.99

Smoking

12 (71%)

7 (39%)

0.0922

Lipid lowering agents

3 (18%)

14 (78%)

0.0006

Beta blockers

5 (29%)

9 (50%)

0.3053

Calcium channel blockers

1 (6%)

3 (17%)

0.6026

ACEI/ARB

3 (18%)

7 (39%)

0.2642

  1. Ascending aorta specimens were procured from organ donors (nondilated) and patients undergoing aortic aneurysm repair (aneurysm). Continuous variables are represented as mean ± SD and categorical variables are represented as number of subjects and percentage of total subjects. Comparisons of continuous variables are by Mann–Whitney test and of categorical variables by Fisher’s exact test.
  2. ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin II receptor blockers.
Back to article page