Table 5 A comparison between previously suggested segmentation algorithms and the Livelayer software.

From: Livelayer: a semi-automatic software program for segmentation of layers and diabetic macular edema in optical coherence tomography images

Algorithm’s name

Simplicity and availability

Processing time

Handling errors

Handling huge data

Extra notes

OCT explorer (Iowa Reference Algorithm)39,40,41

Almost simple

Freely available

Automatic (less than 10 s)

Including an error correction functionality—editing a boundary on one slice considerably affects other boundaries and slices

Yes

An integrated software package—Accepting various file formats—not very good at low-quality, vessel containing OCTs

OCTMarker20

Almost simple

Freely available

Automatic (less than 5 s)

Including an error correction functionality

Yes

An integrated software package—capable of segmenting very few retinal layers (approximately 2 or 3 layers)

EdgeSelect16

Not available

Semi-automatic

Not discussed

Not an integrated software package—only 4 boundaries segmented

SAMIRIX20

Not available

Semi-automatic

Not discussed

An integrated software package—accepting only one file format—capable of segmenting 9 retinal boundaries

Livelayer (our proposed)

Quite simple

Freely available

Semi-automatic (roughly 60 s)

Including an error correction functionality

Yes

An integrated software package—accepting 3 file formats—capable of segmenting 9 retinal boundaries—Exact in low-quality OCTs