Figure 5
From: The structure-based cancer-related single amino acid variation prediction
Boxplots of the microenvironment descriptors in the ASP that are altered to the TYR subgroup. All microenvironment descriptors are divided into nine groups: (a) atoms in the SAV chain; (b) atoms in whole protein; (c) atoms in other chains or molecules; (d) H-group; (e) V-group; (f) Z-group; (g) P-group; (h) F-group; and (i) E-group. The white and grey boxes represent the distribution of cancer-related and neutral SAVs. Red-framed boxes indicate that two sample z-testing revealed a significant difference between cancer-related and neutral SAVs, with a 95% confidence interval (z score > 1.96, p < 0.05). Labels of descriptors selected by the genetic algorithm are bolded in the x-axis. Star symbols denote the D227Y cases in CD23.
