Figure 6
From: The structure-based cancer-related single amino acid variation prediction

Protein structure of the human skeletal calsequestrin. The structure of CASQ (PDB ID: 3UOM)89 in the cyan-colored cartoon is drawn by PyMOL. All of the yellow bubbles are Ca2+ in CASQ. Three Ca2+ binding residues are highlighted with sticks in deep pink. E194G is a cancer-related SAV.