Table 4 List of descriptors in the microenvironment-based feature set.

From: The structure-based cancer-related single amino acid variation prediction

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Feature name

#

Feature name

1

WCN: \(C_{\alpha }\) atoms in SAV chain

17

WCN: Z-high polarizability (KMHFRYW)

2

WCN: Nitrogen atoms in SAV chain

18

WCN: P-low polarity (LIFWCMVY)

3

WCN: Oxygen atoms in SAV chain

19

WCN: P-neutral polarity (PATGS)

4

WCN: \(C_{\alpha }\) atoms in whole protein

20

WCN: P-high polarity (HQRKNED)

5

WCN: Nitrogen in whole protein

21

WCN: F-acidic (DE)

6

WCN: Oxygens in whole protein

22

WCN: F-basic (HKR)

7

WCN: \(C_{\alpha }\) atoms in other chains

23

WCN: F-polar (CGNQSTY)

8

WCN: Atoms in other molecules

24

WCN: F-nonpolar (AFILMPVW)

9

WCN: H-polar (RKEDQN)

25

WCN: E-acidic (DE)

10

WCN: H-neutral (GASTPHY)

26

WCN: E-basic (HKR)

11

WCN: H-hydrophobic (CVLIMFW)

27

WCN: E-aromatic (FWY)

12

WCN: V-small (GASCTPD)

28

WCN: E-amide (NQ)

13

WCN: V-medium (NVEQIL)

29

WCN: E-small hydroxyl (ST)

14

WCN: V-large (MHKFRYW)

30

WCN: E-sulfur-containing (CM)

15

WCN: Z-low polarizability (GASDT)

31

WCN: E-aliphatic 1 (AGP)

16

WCN: Z-neutral (PATGS)

32

WCN: E-aliphatic 2 (ILV)