Table 6 The five-fold cross-validation performance values in the training set of the CanSavPrewm system for each wild-type (WT) residue and the total (bolded).
From: The structure-based cancer-related single amino acid variation prediction
WT | TP | TN | FP | FN | Accuracy | Sensitivity | Specificity | MCC | Precision | F1 score |
|---|---|---|---|---|---|---|---|---|---|---|
ALA | 119 | 616 | 41 | 68 | 0.8709 | 0.6364 | 0.9376 | 0.6081 | 0.7438 | 0.6859 |
CYS | 43 | 93 | 4 | 2 | 0.9577 | 0.9556 | 0.9588 | 0.9040 | 0.9149 | 0.9348 |
ASP | 160 | 375 | 37 | 56 | 0.8519 | 0.7407 | 0.9102 | 0.6664 | 0.8122 | 0.7748 |
GLU | 212 | 341 | 67 | 42 | 0.8353 | 0.8346 | 0.8358 | 0.6602 | 0.7599 | 0.7955 |
PHE | 67 | 118 | 9 | 18 | 0.8726 | 0.7882 | 0.9291 | 0.7331 | 0.8816 | 0.8323 |
GLY | 192 | 406 | 31 | 44 | 0.8886 | 0.8136 | 0.9291 | 0.7528 | 0.8610 | 0.8366 |
HIS | 69 | 182 | 6 | 8 | 0.9472 | 0.8961 | 0.9681 | 0.8710 | 0.9200 | 0.9079 |
ILE | 97 | 428 | 9 | 19 | 0.9494 | 0.8362 | 0.9794 | 0.8436 | 0.9151 | 0.8739 |
LYS | 80 | 258 | 5 | 18 | 0.9363 | 0.8163 | 0.9810 | 0.8357 | 0.9412 | 0.8743 |
LEU | 154 | 292 | 29 | 24 | 0.8938 | 0.8652 | 0.9097 | 0.7702 | 0.8415 | 0.8532 |
MET | 55 | 199 | 3 | 8 | 0.9585 | 0.8730 | 0.9851 | 0.8835 | 0.9483 | 0.9091 |
ASN | 78 | 333 | 7 | 12 | 0.9558 | 0.8667 | 0.9794 | 0.8643 | 0.9176 | 0.8914 |
PRO | 150 | 324 | 39 | 50 | 0.8419 | 0.7500 | 0.8926 | 0.6512 | 0.7937 | 0.7712 |
GLN | 68 | 200 | 12 | 15 | 0.9085 | 0.8193 | 0.9434 | 0.7714 | 0.8500 | 0.8344 |
ARG | 216 | 1,189 | 59 | 112 | 0.8915 | 0.6585 | 0.9527 | 0.6538 | 0.7855 | 0.7164 |
SER | 202 | 376 | 56 | 15 | 0.8906 | 0.9309 | 0.8704 | 0.7724 | 0.7829 | 0.8505 |
THR | 118 | 490 | 15 | 32 | 0.9282 | 0.7867 | 0.9703 | 0.7907 | 0.8872 | 0.8339 |
VAL | 97 | 681 | 14 | 59 | 0.9142 | 0.6218 | 0.9799 | 0.6912 | 0.8739 | 0.7266 |
TRP | 23 | 41 | 1 | 1 | 0.9697 | 0.9583 | 0.9762 | 0.9345 | 0.9583 | 0.9583 |
TYR | 47 | 169 | 7 | 17 | 0.9000 | 0.7344 | 0.9602 | 0.7356 | 0.8704 | 0.7966 |
TOTAL | 2,247 | 7,111 | 451 | 620 | 0.8973 | 0.7837 | 0.9404 | 0.7382 | 0.8328 | 0.8075 |