Table 1 Baseline clinical characteristics of 107 patients with IgG4-related disease.
Overall | Treatment | |||
|---|---|---|---|---|
n = 107 | (−) | (+) | P value* | |
n = 27 | n = 80 | |||
Age | 67 (59, 73) | 70 (60, 78) | 66 (59, 72) | 0.144 |
Male gender (%) | 68 | 78 | 65 | 0.243 |
Allergy (%) | 56 | 70 | 51 | 0.116 |
Serum IgG4 level (mg/dL) | 486 (220, 991) | 361 (187, 1,040) | 495 (254, 975) | 0.507 |
Serum IgG level (mg/dL) | 1951 (1531, 2872) | 1960 (1512, 2655) | 1950 (1535, 2936) | 0.637 |
Serum IgE level (IU/mL) | 486 (190, 1231) | 755 (122, 1764) | 474 (235, 1036) | 0.670 |
Serum IgG4/IgE ratio | 0.99 (0.38, 3.24) | 0.54 (0.22, 4.28) | 1.11 (0.40, 3.15) | 0.494 |
Serum C3 level (mg/dL) | 90 (76, 110) | 90 (76, 106) | 94 (76, 110) | 0.810 |
Serum C4 level (mg/dL) | 22 (14, 27) | 22 (19, 28) | 21 (14, 27) | 0.363 |
Serum CH50 level (IU/L) | 51 (38, 58) | 50 (39, 56) | 51 (35, 59) | 0.976 |
Serum CRP level (mg/dL) | 0.1 (0.0, 0.3) | 0.1 (0.0, 0.2) | 0.1 (0.0, 0.3) | 0.599 |
Serum creatinine level (mg/dL) | 0.79 (0.64, 1.00) | 0.75 (0.65, 0.94) | 0.80 (0.60, 1.05) | 0.415 |
Eosinophil count (/μL) | 204 (118, 426) | 180 (119, 598) | 230 (118, 422) | 0.766 |
RF positivity (%) | 20 | 17 | 21 | 0.772 |
ANA positivity (%) | 14 | 11 | 15 | 0.755 |
Pancreatic lesion (%) | 26 | 19 | 29 | 0.448 |
Salivary gland lesion (%) | 58 | 67 | 55 | 0.369 |
Ophthalmic lesion (%) | 47 | 26 | 54 | 0.015 |
Renal lesion (%) | 21 | 4 | 26 | 0.012 |
Vascular lesion (%) | 27 | 30 | 26 | 0.804 |
Retroperitoneal lesion (%) | 8 | 4 | 10 | 0.444 |
Lung lesion (%) | 25 | 11 | 30 | 0.072 |
Number of involved organs | 2 (1, 4) | 1 (1, 3) | 3 (2, 4) | 0.001 |
IgG4-RD responder index | 12 (9, 18) | 9 (6, 15) | 12 (9, 18) | 0.048 |
