Table 1 Clinical characteristics of autosomal-dominant spinocerebellar ataxia patients and serum neurofilament light chain levels.
From: Serum neurofilament light chain as a severity marker for spinocerebellar ataxia
Subject characteristics | Total (n = 49) |
|---|---|
Age—year | 44.0 (34.0–50.0) |
Female sex—no. (%) | 31 (63.3) |
SCA type—no. (%) | |
SCA 1 | 2 (4.1) |
SCA 2 | 19 (38.8) |
SCA 3 | 13 (26.5) |
SCA 6 | 9 (18.4) |
SCA 7 | 4 (8.2) |
SCA 17 | 2 (4.1) |
Trinucleotide repeat number | 42.0 (38.0–65.0) |
Disease onset—year | 38.0 (27.0–46.0) |
Disease duration—year | 5.0 (2.0–7.0) |
SARA (n = 33) | 11.0 (9.0–15.0) |
Serum NfL (pg/mL) | 109.5 (70.1–154.9) |
