Table 2 Patient characteristics and serum neurofilament light chain of autosomal-dominant spinocerebellar ataxia patients and controls.

From: Serum neurofilament light chain as a severity marker for spinocerebellar ataxia

 

AD SCA (n = 49)

Controls (n = 37)

p-value

Age—year (range)

44.0 (34.0–50.0)

42.0 (33.0–49.0)

0.441

Female sex—no. (%)

31 (63.3)

28 (75.7%)

0.220

Serum NfL (range) (pg/mL)

109.5 (70.1–154.9)

41.1 (32.3–57.1)

 < 0.001

  1. Data are reported as the number (percentage), or as the median (interquartile range, IQR).
  2. AD autosomal dominant, SCA spinocerebellar ataxia, NfL chain neurofilament light chain.