Table 2 GRADE summary of findings.
Outcome | Effect (95% CI) | Pooled prevalence (CI 95%) | Number of studies | Number of participants | Certainty of evidence (GRADE) |
|---|---|---|---|---|---|
IL-1 as diagnostic factor for PHLF | – | – | 2 | 23 | Very low |
IL-6 as diagnostic factor for organ dysfunction | MD (95% CI): 230.80 (− 440.46–902.05) | – | 2 | 152 | Very low |
PreHA as a diagnostic factor for PHLF | Sensitivity: 45.16% (27.32–63.97%) Specificity: 93.50% (89.14–96.49%) | 13.42% (9.30–18.50%) | 2 | 231 | Very low |
PostHA as diagnostic factor for PHLF | Sensitivity: 100% (83.89–100%) Specificity: 93.75% (88.47–97.10%) | 12.73% (8.05–18.79%) | 3 | 165 | Very low |
HGF as diagnostic factor for PHLF | – | – | 1 | 24 | Very low |
VEGF as diagnostic factor for PHLF | – | – | 5 | 250 | Very low |
