Table 5 Association between the presence of thyroid cysts and hypertension by the existence of atherosclerosis in participants without taking anti-hypertensive medication.

From: Association between thyroid cysts and hypertension by atherosclerosis status: a cross-sectional study

 

Atherosclerosis (−)

Atherosclerosis (+)

Interaction

Thyroid cyst

p

Thyroid cyst

p

(−)

(+)

(−)

(+)

Systolic hypertension

Number of participants

812

349

 

59

46

  

Number of case (%)

83 (10.2)

57 (16.3)

 

14 (23.7)

8 (17.4)

  

Model 1 OR (95% CI)

Ref

1.61 (1.10, 2.36)

0.014

Ref

0.65 (0.24, 1.73)

0.385

0.109

Model 2 OR (95% CI)

Ref

1.70 (1.15, 2.52)

0.008

Ref

0.46 (0.14, 1.54)

0.207

0.0497

Model 3 OR (95% CI)

Ref

1.71 (1.15, 2.53)

0.008

Ref

0.36 (0.10, 1.37)

0.135

0.044

Diastolic hypertension

Number of participants

812

349

 

59

46

  

Number of case (%)

46 (5.7)

20 (5.7)

 

5 (8.5)

3 (6.5)

  

Model 1 OR (95% CI)

Ref

1.07 (0.61, 1.86)

0.825

Ref

0.88 (0.19, 4.08)

0.874

0.711

Model 2 OR (95% CI)

Ref

1.11 (0.63, 1.96)

0.712

Ref

0.55 (0.09, 3.28)

0.509

0.450

Model 3 OR (95% CI)

Ref

1.13 (0.64, 1.99)

0.683

Ref

0.58 (0.09, 3.96)

0.577

0.397

  1. Model 1: adjusted for sex and age. Model 2: + BMI, smoking status (never, former, current), drinking status (non, often, daily) TG, HDLc, HbA1c. Model 3: + TSH, free T3, free T4. Systolic hypertension was defined as SBP ≥ 140 mmHg while diastolic hypertension was defined as DBP ≥ 90 mmHg. Atherosclerosis was defined atherosclerosis as CIMT ≥ 1.1 mm.
  2. OR odds ratio, CI confidence interval, Ref reference, BMI Body mass index, TG triglycerides, HDLc HDL-cholesterol, HbA1c hemoglobin A1c, TSH thyroid stimulating hormone, T3 triiodothyronine, T4 thyroxine, SBP systolic blood pressure, DBP diastolic blood pressure, CIMT carotid intima-media thickness.
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