Figure 2 | Scientific Reports

Figure 2

From: Prevalence of UL97 gene mutations and polymorphisms in cytomegalovirus infection in the colon associated with or without ulcerative colitis

Figure 2

Schematic diagram of natural polymorphisms and GCV-resistant mutations in pUL97. The kinase domain is located between amino acids 337 and 651. All amino acid positions related to the established GCV-resistance mutations reported in the literature are indicated below. Interaction region for GCV is defined by the location of resistance mutations detected within the kinase domain so far (405, 460, 466, 520, 590, 591, 592, 594, 595, 596, 597, 598, 599, 600, 601, 603, 607)34. Amino acid positions related to polymorphisms detected in this study are indicated above. Natural polymorphisms that have been reported in the literature are indicated in bold32.

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