Table 2 Logistic regression analysis of the pre-treatment variables associated with poor prognosis of extraocular muscle movement limitation in the restrictive myopathy associated with thyroid eye disease.

From: Prognostic factors of restrictive myopathy in thyroid eye disease

Parameters

Univariate analysis

Multivariate analysis

OR

95% CI

P

OR

95% CI

P*

Age, years

0.99

0.94–1.04

0.614

0.91

0.81–1.03

0.138

Sex, M:F

0.94

0.36–2.51

0.909

0.55

0.30–9.94

0.546

Disease onset, mo

1.11

0.95–1.31

0.191

1.01

0.74–1.37

0.953

CAS

0.91

0.68–1.22

0.540

   

Diplopia grade

1.12

0.66–1.90

0.681

   

TSH, μIU/mL

0.99

0.91–1.08

0.89

   

T3, ng/dL

1.01

0.99–1.02

0.483

   

fT4, ng/dL

0.61

0.25–1.45

0.259

0.19

0.03–1.18

0.075

TSAb, 10%

1.06

1.01–1.11

0.028

1.09

1.00–1.18

0.044

TSHR-Ab, 10 IU/L

1.00

0.89–1.14

0.975

   

Treatment, n

Conservative

0.97

0.13–7.32

0.975

   

Oral PD

0.96

0.34–2.67

0.929

   

IV methylPD

0.43

0.13–1.43

0.166

0.80

0.11–5.81

0.827

Radiotherapy

1.09

0.39–3.02

0.867

   
  1. mo month, M male, F female, CAS clinical activity score, TSH thyroid stimulating hormone, T3 triiodothyronine, fT4 free thyroxine, TSAb thyroid-stimulating antibody, TSHR-Ab thyroid stimulating hormone receptor antibody, n number, IV methylPD intravenous methylprednisolone, CI confidence interval, OR odds ratio.
  2. *Variables with P < 0.20 in the univariate analysis, age, and sex were included in the multivariate analysis.