Table 3 Cause of death in relation to year of birth.
From: The value of autopsy in preterm infants at a Swedish tertiary neonatal intensive care unit 2002–2018
Both periods | Period 1 2002–2009 | Period 2 2011–2018 | p value | |
|---|---|---|---|---|
Total deaths (n) | 265 | 105 | 160 | – |
Total deaths with determined cause of death (n) | 260 | 101 | 159 | – |
Cause of death—number of cases (% of total) | n | n (%) | n (%) | |
|---|---|---|---|---|
Congenital anomalies | 18 | 10 (9.9) | 8 (5.0) | 0.132 |
Neural anomaly | 3 | 2 (2.0) | 1 (0.6) | 0.562 |
Cardiac anomaly | 3 | 2 (2.0) | 1 (0.6) | 0.562 |
Other anomaly | 9 | 3 (3.0) | 6 (3.8) | 1.000 |
Chromosomal abnormalities | 3 | 3 (3.0) | 0 (0.0) | 0.058 |
Asphyxia | 17 | 10 (9.6) | 7 (4.4) | 0.080 |
Intrauterine | 8 | 4 (4.0) | 4 (2.5) | 0.715 |
Perinatal | 8 | 6 (5.9) | 2 (1.3) | 0.059 |
Postnatal | 1 | 0 (0.0) | 1 (0.6) | 1.000 |
Respiratory | 75 | 31 (30.7) | 44 (27.3) | 0.674 |
RDS | 10 | 7 (6.9) | 3 (1.9) | 0.039 |
BPD | 12 | 5 (5.0) | 7 (4.4) | 0.837 |
Pulmonary hypoplasia | 20 | 8 (7.9) | 12 (7.5) | 0.912 |
PPHN | 10 | 5 (5.0) | 5 (3.1) | 0.461 |
Pneumothorax | 5 | 1 (1.0) | 4 (2.5) | 0.651 |
Haemothorax | 4 | 3 (3.0) | 1 (0.6) | 0.302 |
Miscellaneous | 14 | 2 (2.0) | 12 (7.5) | 0.087 |
IVH | 22 | 13 (12.9) | 9 (5.7) | 0.042 |
Infection/sepsis | 41 | 19 (18.8) | 22 (13.8) | 0.283 |
Early | 11 | 3 (3.0) | 8 (5.0) | 0.537 |
Late | 30 | 16 (15.8) | 14 (8.8) | 0.083 |
NEC | 45 | 5 (5.0) | 40 (25.2) | < 0.001 |
NEC with Sepsis | 16 | 2 (2.0) | 14 (8.8) | 0.053 |
NEC without sepsis | 29 | 3 (3.0) | 26 (16.4) | 0.001 |
Other | 42 | 13 (12.9) | 29 (18.2) | 0.252 |
Shock/anemia/bleeding | 8 | 1 (1.0) | 7 (4.4) | 0.156 |
Volvulus/malrotation | 4 | 1 (1.0) | 3 (1.9) | 1.000 |
Isolated spontaneous intestinal perforation | 4 | 0 (0.0) | 4 (2.5) | 0.160 |
Metabolic/electrolyte/endocrine disorders | 4 | 2 (2.0) | 2 (1.3) | 0.643 |
Tumor | 3 | 0 (0.0) | 3 (1.9) | 0.285 |
Twin-twin transfusion syndrome | 2 | 2 (1.0) | 1 (0.6) | 0.562 |
CNS-related | 3 | 1 (1.0) | 2 (1.3) | 1.000 |
Other | 8 | 4 (4.0) | 4 (2.5) | 0.715 |
Prematurity | 3 | 2 (2.0) | 1 (0.6) | 0.562 |
Unknown | 2 | 0 (0.0) | 2 (1.3) | 0.523 |
