Figure 4

Clinical scores. Lysholm score (total) and KOOS (ADL) ranged from 0 to 100, with lower scores indicating more severe symptoms. NRS (walking) ranged from 0 to 10, with higher scores indicating more severe symptoms. MSCs were injected at time 0 and again at 15 weeks (arrow). At time 0 and 15 weeks, clinical scores were evaluated just before the MSC injections. Data are shown as median and IQR. The sample number is 8 for each outcome. *p < 0.05, **p < 0.01 with a value at time 0. Alterations in cartilage quantification before and after injections of mesenchymal stem cells into osteoarthritic knees.