Table 3 Effects of OEO, main components, and positive control (apocynin) at different concentrations (5 and 10 µg/ml) on ROS production and NOX activity in LPS-stimulated macrophages.

From: In-vitro, in-vivo, and in-silico assessment of radical scavenging and cytotoxic activities of Oliveria decumbens essential oil and its main components

Treatment

ROS(× 1000)

NOX activity

Control

15.7 ± 0.86b

11.7 ± 0.64a

LPS

27.6 ± 1.32ef

32.0 ± 1.54f

LPS/Apo10

17.6 ± 0.77bc

13.3 ± 0.59ab

LPS/OEO5

14.3 ± 0.72b

22.3 ± 1.12d

LPS/OEO10

9.7 ± 0.57a

13.7 ± 0.81b

LPS/Thymol5

20.3 ± 1.14c

20.3 ± 1.14d

LPS/Thymol10

16.0 ± 0.82b

14.3 ± 0.73bc

LPS/Carvacrol5

17.3 ± 0.85b

16.0 ± 0.78c

LPS/Carvacrol10

10.3 ± 0.57a

10.0 ± 0.55a

LPS/Cymene5

25.0 ± 1.40de

25.6 ± 1.43e

LPS/Cymene10

24.6 ± 1.30cd

22.6 ± 1.20d

LPS/Terpinene5

29.9 ± 1.50f

25.7 ± 1.29e

LPS/Terpinene10

25.0 ± 1.43d

22.7 ± 1.29de

  1. The values are expressed as means ± SDs for three replicate experiments. Mean values with different letters within a column are significantly different by the Tukey test at (p < 0.05). This test classifies the groups into letters. Groups that have little significant difference have similar letters and those with more significant difference receive different letters.