Table 4 Effects of OEO, main components at different concentrations (5 and 10 µg/ml), and positive control (L-NAME, 1.3 μg/ml) on NO production and NOS activity in LPS-stimulated macrophages.

From: In-vitro, in-vivo, and in-silico assessment of radical scavenging and cytotoxic activities of Oliveria decumbens essential oil and its main components

Treatment

NO

NOS activity

Control

27.0 ± 1.22de

13.3 ± 0.60a

LPS

38.0 ± 2.13g

42.3 ± 2.37f

LPS/L-Name1.3

21.0 ± 1.22c

17.3 ± 1.00b

LPS/OEO5

21.3 ± 1.26c

31.7 ± 1.87cd

LPS/OEO10

14.7 ± 0.84a

17.6 ± 1.00b

LPS/Thymol5

25.6 ± 1.41d

28.3 ± 1.56c

LPS/Thymol10

18.0 ± 1.04b

17.3 ± 1.00b

LPS/Carvacrol5

21.7 ± 1.17d

19.0 ± 1.03b

LPS/Carvacrol10

12.0 ± 0.70a

11.3 ± 0.66a

LPS/Cymene5

29.0 ± 1.51e

38.7 ± 2.01ef

LPS/Cymene10

24.7 ± 1.33d

32.7 ± 1.77d

LPS/Terpinene5

32.7 ± 1.87f

36.7 ± 2.13e

LPS/Terpinene10

28.0 ± 1.43e

33.6 ± 1.71de

  1. The values are expressed as means ± SDs for three replicate experiments. Mean values with different letters within a column are significantly different by the Tukey test at (p < 0.05). This test classifies the treated groups into letters. Groups that have little significant difference have similar letters and those with more significant difference receive different letters.
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