Table 1 Baseline demographics and laboratory characteristics of the primary cohort.

From: Machine learning application for the prediction of SARS-CoV-2 infection using blood tests and chest radiograph

 

COVID-19

Other viral PNA

Bacterial PNA

Clinical PNA

Other infections

Other diseases

Demographics

Total, n

447

405

1515

1862

256

663

Female, n (%)

202 (45)

192 (47)

570 (38)

865 (46)

138 (54)

276 (42)

Age, years

      

Mean ± SD

42 ± 17

53 ± 22

74 ± 17

73 ± 19

45 ± 21

61 ± 21

Median (IQR)

39 (28–57)

52 (35–70)

77 (65–87)

79 (62–88)

39 (29–59)

64 (46–79)

16–35

174 (39)

101 (25)

46 (3)

117 (6)

104 (41)

105 (16)

35–50

113 (25)

87 (21)

85 (6)

147 (8)

62 (24)

82 (12)

50–65

115 (26)

83 (20)

237 (16)

281 (15)

37 (14)

152 (23)

 > 65

45 (10)

134 (33)

1147 (76)

1317 (71)

53 (21)

324 (49)

Haemoglobin g/dL

Missing, n (%)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

Mean ± SD

13.9 ± 1.4

12.9 ± 2.2

11.1 ± 2.4

11.4 ± 2.5

13.2 ± 2.0

12.0 ± 2.6

Median (IQR)

13.9 (13.0–15.0)

13.2 (11.7–14.6)

11.1 (9.3–12.8)

11.7 (9.7–13.2)

13.4 (12.1–14.5)

12.4 (10.3–14.0)

Haematocrit

Missing, n (%)

0 (0)

0 (0)

0 (0)

1 (0)

0 (0)

0 (0)

Mean ± SD

0.4 ± 0.0

0.4 ± 0.1

0.3 ± 0.1

0.3 ± 0.1

0.4 ± 0.1

0.4 ± 0.1

Median (IQR)

0.4 (0.4–0.4)

0.4 (0.4–0.4)

0.3 (0.3–0.4)

0.4 (0.3–0.4)

0.4 (0.4–0.4)

0.4 (0.3–0.4)

WBC, 109/L

Missing, n (%)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

Mean ± SD

5.5 ± 1.9

8.8 ± 4.8

12.6 ± 12.9

11.3 ± 6.7

9.4 ± 5.5

11.5 ± 21.5

Median (IQR)

5.2 (4.3–6.4)

7.7 (6.0–10.2)

11.1 (7.5–15.4)

9.8 (7.1–13.7)

7.7 (6.3–10.5)

9.0 (6.8–12.4)

Lymphocyte, 109/L

Missing, n (%)

4 (1)

48 (12)

97 (6)

108 (6)

17 (7)

43 (6)

Mean ± SD

1.3 ± 0.6

1.4 ± 0.8

1.1 ± 2.1

1.2 ± 1.5

1.7 ± 1.1

1.4 ± 2.5

Median (IQR)

1.3 (0.9–1.7)

1.3 (0.8–1.8)

0.9 (0.5–1.4)

1.0 (0.6–1.5)

1.6 (1.0–2.1)

1.2 (0.7–1.7)

Monocyte 109/L

Missing, n (%)

4 (1)

48 (12)

100 (7)

108 (6)

17 (7)

44 (7)

Mean ± SD

0.5 ± 0.2

0.6 ± 0.4

0.7 ± 1.0

0.8 ± 1.8

0.6 ± 0.4

0.7 ± 0.9

Median (IQR)

0.5 (0.3–0.6)

0.6 (0.4–0.8)

0.6 (0.4–0.9)

0.6 (0.4–0.9)

0.5 (0.3–0.7)

0.6 (0.4–0.9)

Neutrophil 109/L

Missing, n (%)

4 (1)

48 (12)

97 (6)

108 (6)

17 (7)

43 (6)

Mean ± SD

3.6 ± 1.7

6.7 ± 4.8

10.4 ± 7.4

9.1 ± 5.5

7.1 ± 5.6

8.4 ± 5.7

Median (IQR)

3.3 (2.4–4.4)

5.4 (3.9–7.8)

8.9 (5.8–13.5)

7.8 (5.1–11.6)

5.2 (3.9–8.3)

6.7 (4.5–10.6)

Platelet 109/L

Missing, n (%)

0 (0)

0 (0)

4 (0)

2 (0)

0 (0)

0 (0)

Mean ± SD

221.2 ± 74.1

233.3 ± 87.4

246.0 ± 117.7

241.2 ± 108.7

234.1 ± 81.2

255.4 ± 108.4

Median (IQR)

205.0 (171.0–259.0)

223.0 (173.0–280.0)

231.0 (169.5–307.0)

224.5 (168.0–294.0)

233.0 (179.0–281.2)

236.0 (188.0–301.0)

CRP mg/dL

Missing, n (%)

48 (11)

181 (45)

610 (40)

638 (34)

122 (48)

292 (44)

Mean ± SD

1.9 ± 4.0

4.9 ± 7.7

9.9 ± 9.6

7.4 ± 8.1

5.7 ± 9.4

5.9 ± 8.0

Median (IQR)

0.4 (0.2–1.4)

1.9 (0.4–6.0)

7.1 (2.1–15.2)

4.9 (1.1–11.0)

0.7 (0.1–7.0)

2.1 (0.3–8.8)

LDH U/L

Missing, n (%)

31 (7)

250 (62)

936 (62)

1020 (55)

146 (57)

347 (52)

Mean ± SD

208.9 ± 74.8

238.1 ± 124.7

371.9 ± 625.5

287.0 ± 344.9

198.5 ± 73.4

296.8 ± 500.6

Median (IQR)

186.5 (158.0–237.0)

210.0 (165.0–253.2)

252.6 (193.7–353.0)

226.5 (184.0–290.0)

177.0 (155.5–212.0)

210.5 (178.0–293.2)

  1. SD standard deviation, IQR intequartile range, PNA pneumonia, WBC white blood cell, CRP C-reactive protein, LDH lactate dehydrogenase.