Figure 4

Thioflavin T fluorescence spectra of Aβ42 alone, and after treatment with PIMT and PIMT in presence of AuNSs after (a) 2 h and (b) 24 h. Samples were excited at 440 nm in 20 mM sodium phosphate buffer (pH 7.2). (c)–(f) Confocal microscopic images of Aβ42 fibrils under different conditions, (c) peptide alone, and in presence of (d) PIMT, (e) AuNS100 and (f) PIMT and AuNS100 together.