Figure 5
Peripheral chemoreflex gain is lower in exercise intolerant heart failure rats (HF + EX-inT). (A) Representative traces of whole-body plethysmography from one HF + Sed rat, one HF + EX-T rat, and one HF + EX-inT rat during normoxia (FiO2 21%), hypercapnia (FiCO2 7%), and hypoxia (FiO2 10%). (B) Summary data of hypercapnic ventilatory response HCVR. (C) Summary effects of EX on HVR. Note that HF + EX-inT showed a lower hypoxic ventilatory response (HVR) compared to the HF + Sed rats and HF + EX-T rats. *p < 0.05 vs. HF + Sed; +p < 0.05 vs. HF + EX-T. HF + Sed, n = 6; HF + EX-T, n = 6; HF + EX-inT, n = 6.
