Table 2 Resting ventilatory parameters during normoxia (FiO2 21%), hypoxia (FiO2 10%), and hypercapnia (FiCO2 7%) in HF after 6 weeks of exercise training (EX).

From: Exercise intolerance in volume overload heart failure is associated with low carotid body mediated chemoreflex drive

 

HF + Sed

(N = 5)

HF + EX-T

(N = 5)

HF + EX-inT

(N = 5)

Normoxia

VT (ml/100 g)

0.27 ± 0.01

0.24 ± 0.04

0.22 ± 0.04

Rf (breaths/min)

83.29 ± 5.18

87.89 ± 12.60

88.75 ± 9.96

Ve (mL/min 100 g)

22.62 ± 2.30

21.18 ± 0.83

19.59 ± 2.20

Ti (ms)

278.10 ± 53.21

276.90 ± 44.40

245.60 ± 15.46

Te (ms)

420.40 ± 23.48

420.60 ± 138.60

438.70 ± 73.37

Ttot (ms)

698.40 ± 54.26

697.40 ± 103.70

684.20 ± 67.07

PiF (ml/s)

9.69 ± 3.34

8.08 ± 2.32

8.38 ± 1.58

PeF (ml/s)

5.755 ± 1.56

5.33 ± 1.54

4.51 ± 0.95

Hypercapnia

VT(ml/100 g)

0.37 ± 0.08

0.32 ± 0.02

0.30 ± 0.03*

Rf (breaths/min)

201.8 ± 47.99

161.50 ± 16.68*

181.20 ± 29.69

Ve (mL/min 100 g)

74.74 ± 12.98

51.57 ± 3.98*

55.28 ± 4.07*

Ti (ms)

155.70 ± 23.01

180.10 ± 18.12*

204.40 ± 16.02*

Te (ms)

177.50 ± 55.20

197.70 ± 28.70

172.30 ± 15.67

Ttot (ms)

333.10 ± 97.63

377.90 ± 36.83

376.70 ± 28.69

PiF (ml/s)

18.66 ± 2.80

14.18 ± 1.63*

12.49 ± 2.78*

PeF (ml/s)

15.97 ± 3.09

12.57 ± 2.21*

10.03 ± 2.21*

Hypoxia

VT (ml/100 g)

0.32 ± 0.03

0.35 ± 0.04

0.27 ± 0.07+

Rf (breaths/min)

193.20 ± 21.31

174.20 ± 14.82

144.70 ± 16.06*+

Ve (mL/min 100 g)

61.62 ± 4.34

60.61 ± 4.05

40.86 ± 14.14*+

Ti (ms)

149.40 ± 13.37

151.30 ± 16.37

194.20 ± 19.57*

Te (ms)

170.50 ± 21.66

184.40 ± 17.90

227.80 ± 31.26*+

Ttot (ms)

320.00 ± 33.30

335.70 ± 21.52

422.00 ± 46.40*+

PiF (ml/s)

18.31 ± 2.82

17.33 ± 2.37

10.17 ± 2.41*+

PeF (ml/s)

17.5 ± 2.38

16.17 ± 2.23

11.69 ± 2.97*+

  1. Values are expressed as mean ± SEM.
  2. T: tolerant; inT: intolerant; VT: tidal volume; Rf: respiratory frequency; Ve: minute ventilation; Ti: inspiratory time; Te: expiratory time; Ttot: total respiratory time; PiF: peak inspiratory flow; and PeF: peak expiratory flow.
  3. One-way ANOVA, Sidak post hoc analysis. *vs. HF + Sed, +vs. HF + EX-T, p < 0.05.