Table 2 Crude and adjusted odd ratios (95% confidence interval) of date of statin prescription (1 year) for hearing impairment with stratified subgroup according age and sex.

Characteristics	Odds ratios for hearing impairment
Characteristics	Crude†	P value	Model 1†‡	P value	Model 2†§	P value
Total participants (n = 21,935)
Statin prescription (1 year)	0.98 (0.90–1.05)	0.521	0.94 (0.86–1.02)	0.115	0.94 (0.86–1.02)	0.118
Age < 70 years old (n = 11,910)
Statin prescription (1 year)	1.04 (0.93–1.17)	0.498	1.00 (0.89–1.13)	0.959	1.03 (0.89–1.13)	0.958
Age ≥ 70 years old (n = 10,025)
Statin prescription (1 year)	0.93 (0.84–1.03)	0.162	0.89 (0.80–1.00)	0.040*	0.89 (0.80–0.99)	0.039*
Men (n = 13,255)
Statin prescription (1 year)	0.93 (0.84–1.04)	0.190	0.89 (0.79–0.99)	0.039*	0.88 (0.79–0.99)	0.037*
Women (n = 8,680)
Statin prescription (1 year)	1.03 (0.92–1.15)	0.613	0.99 (0.88–1.12)	0.901	0.99 (0.88–1.12)	0.917

Abbreviations: CCI, Charlson Comorbidity Index;
*Conditional logistic regression analysis, Significance at P < 0.05.
^†Stratified model for age, sex, income, and region of residence.
^‡Model 1 was adjusted for SBP, DBP, fasting blood glucose, total cholesterol, hemoglobin, and dyslipidemia.
^§Model 2 was adjusted for model 1 plus obesity, smoking, alcohol consumption, and CCI scores.

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