Figure 1

Metabolomic heat maps. Left-side, maternal (controls [n = 88], FGR [n = 44], PE [n = 40], PE + FGR [n = 50]); right-side, cord blood (controls [n = 86], FGR [n = 43], PE [n = 37], PE + FGR [n = 50]) plasma samples. A z-score transformation was performed on the intensity of each metabolite across all the study groups and each group’s mean z-score is displayed in the heatmap. Rows represent metabolites and columns represent samples. Samples and metabolites are clustered by Euclidean distance and Ward linkage. CT, controls; FGR, fetal growth restriction; PE, preeclampsia; VLDL, Very low-density lipoprotein; IDL, Intermediate-density lipoprotein; LDL, Low-density lipoprotein; HDL, High-density lipoprotein; C, cholesterol; TG, triglycerides; Glc/GalNAc, N-acetylglucosamine and N-acetylgalactosamine bonds glycoproteins.