Figure 1
From: Genetic overlap and causal associations between smoking behaviours and mental health
Heat map showing genetic correlations between smoking behaviours, psychotic experiences and psychiatric disorders. PENS Psychotic experiences (PE) and negative symptom traits; NA indicates that genetic correlations could not be computed due to low SNP-heritability or sample size; *indicates statistically significant genetic correlations at p < .05; **indicates significance at FDR < .05 using Benjamini–Hochberg correction for 60 tests; Genetic correlations reported using unconstrained LD score regression intercept between phenotypes with sample overlap (for example, smoking behaviour and major depression GWASs contained participants from the UK Biobank, and smoking behaviours and adolescent PENS contained participants from ALSPAC). Note that age of smoking initiation was coded in the direction of lower scores reflecting younger ages of initiation. Note that current smoking cases are current smokers (compared to ex-smokers).
