Figure 6

Ex vivo [18F]FTC-146 autoradiography comparison of blarcamesine and PRE-084 binding at 1 mg/kg PO in WT mice. Both S1R agonists showed similar S1R blocking in various brain regions in WT mice (N = 4–5 per group). Levels of binding were compared with those of control WT mouse. Error bars show standard deviation.