Figure 1
Serum miR-513b-5p and related gene expression in participants. Quantitative RT-PCR assay was used to detected gene expression. (A) miR-513b-5p, COL1A1 and COL1A2 expression. (B) Inflammatory cytokine of TNF-α, IL-1β and IL-6 mRNA expression. (C) MMP2, MMP3, MMP9 and TIMP4 mRNA expression. UA, unrupture aneurysm (n = 100); RA, rupture aneurysm (n = 100); control (n = 100). MiR-513b-5p expression was normalized to cel-miR-39, other mRNA expression was normalized to GAPDH. All of the data are presented as the mean ± standard deviation. Compared with control group, *p < 0.05; **p < 0.01 and ***p < 0.001. Compared with UA group, #p < 0.05 and ###p < 0.001. Mann–Whitney U test with two-sided was performed.
