Table 2 Participants’ clinical characteristics.

From: MicroRNA-513b-5p targets COL1A1 and COL1A2 associated with the formation and rupture of intracranial aneurysm

Factors

Control (n = 100)

Unrupture IA (n = 100)

Rupture IA (n = 100)

p value

Age (years)

60 (53–66)

59 (50–67)

55.5 (49.25–62.75)

0.123a

Men

57 (57%)

53 (53%)

50 (50%)

0.609b

CRP (mg/L)

2.81 (1.6–7.09)

4 (2.22–8.37)*

8.64 (3–19.47)*,#

< 0.001a

TC (mmol/L)

4.42 ± 0.12

4.33 ± 0.11

4.35 ± 0.11

0.851c

LDL-C (mmol/L)

2.99 ± 0.10

2.68 ± 0.07

2.81 ± 0.10

0.077c

HDL-C (mmol/L)

1.06 (0.87–1.29)

1.19 (0.88–1.56)*

1.19 (0.96–1.48) *

0.027a

GLU (mmol/L)

5.36 (4.88–6.66)

4.98 (4.46–5.63)*

6.29 (5.31–7.56)*,#

< 0.00a

TG (mmol/L)

1.27 (0.91–1.83)

1.46 (0.91–1.75)

1.08 (0.76–1.48)*,#

0.021a

UA (mmol/L)

356 (255–405.75)

304 (232–369.75)*

242 (163.75–323)*,#

< 0.001a

HbA1c (mmol/L)

6.1 (5.6–7.5)

6 (5.6–6.67)

5.7 (5.5–6)*,#

< 0.001a

Creatinine (μmol/L)

70 (58–81.75)

65 (57–79)*

60 (50–71)*,#

< 0.001a

Hcy (mmol/L)

8.2 (9.85–13.8)

8.05 (6.25–10.17)*

9.32 (7.8–13.07)#

< 0.001a

BNP (pg/mL)

91.14 (45.08–180.11)

77.09 (42.01–113.09)*

180 (61.48–578.95)*,#

< 0.001a

Hypertension

42 (42%)

40 (40%)

44 (44%)

0.849b

Diabetes mellitus

14 (14%)

19 (19%)

14 (14%)

0.532b

Coronary heart disease

7 (7%)

11 (11%)

8 (8%)

0.578b

cerebral infarction

15 (15%)

14 (14%)

18 (18%)

0.720b

Hypertension + Diabetes mellitus

18 (18%)

11 (11%)

13 (13%)

0.340b

Others

4 (4%)

5 (5%)

3 (3%)

0.769b

Smoking status

   

0.697b

Never

30 (30%)

23 (23%)

28 (28%)

 

Current

26 (26%)

33 (33%)

29 (29%)

 

Previously

21 (21%)

25 (25%)

27 (27%)

 

Occasionally

23 (23%)

19 (19%)

16 (16%)

 

Alcohol drinking

   

0.528b

Never

22 (22%)

28 (28%)

25 (25%)

 

 ≤ 3 times/week

33 (33%)

34 (34%)

34 (34%)

 

 > 4 times/week

15 (15%)

17 (17%)

22 (22%)

 

Occasionally

30 (30%)

21 (21%)

19 (19%)

 

Hunt Hess Grade

0 (0–0)

0 (0–0)*

2 (1–3)*,#

< 0.001a

GCS Grade

0 (0–0)

15 (15–15)*

15 (14–15)*,#

< 0.001a

WFNS Grade

0 (0–0)

1 (1–1)*

1 (1–2)*,#

< 0.001a

mRS

0 (0–0)

0 (0–0)*

0 (0–2)*,#

< 0.001a