Figure 1 | Scientific Reports

Figure 1

From: Taxonomic changes in the gut microbiota are associated with cartilage damage independent of adiposity, high fat diet, and joint injury

Figure 1

Chow-fed MEF and WF-rescued LD mice demonstrate increased diversity when compared to HFD-fed LD mice than WT or chow-fed LD mice, suggesting rescue does not recover taxonomic changes in gut microbiota. Serum levels for endotoxin, or lipopolysaccharide (A). Synovial fluid levels for lipopolysaccharide (B). Operational taxonomic units (OTU) richness (C) Shannon Diversity (D) and Bacteroidetes:Firmicutes Ratio (E) for all groups WT groups are displayed. Animal numbers by group: Chow WT n = 22, Chow LD n = 15, HFD WT n = 17, HFD LD n = 8, MEF-R n = 15, WF-R n = 12. Data were evaluated by one or two-way ANOVA and Tukey or Sidak post-hoc testing. Different letters indicate statistical significance, p < 0.05, such that A: p < 0.05 vs B and C; B: p < 0.05 vs A and C, C: p < 0.05 vs A and B; AB: p > 0.05 vs A and B.

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