Table 1 Two-way ANOVA comparing the effect of FLX on regional MeCP2+ cells in Mecp2 HET and WT mice shown in Figs. 1 and 2.

From: Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin

Brain region

F value (df)

P value

PFC

Genotype

42.36 (1,41)

< 0.0001

Fluoxetine

12.13 (1,41)

0.0012

Interaction

2.27 (1,41)

0.14

M1

Genotype

44.02 (1,40)

< 0.0001

Fluoxetine

8.65 (1,40)

0.005

Interaction

2.19 (1,40)

0.15

M2

Genotype

65.03 (1,40)

< 0.0001

Fluoxetine

9.64 (1,40)

0.004

Interaction

1.66 (1,40)

0.21

CA3

Genotype

64.99 (1,26)

< 0.0001

Fluoxetine

0.818 (1,26)

0.374

Interaction

0.350 (1,26)

0.559

DSTR

Genotype

72.22 (1,40)

< 0.0001

Fluoxetine

5.41 (1,40)

0.025

Interaction

2.86 (1,40)

0.099

VSTR

Genotype

69.66 (1,40)

< 0.0001

Fluoxetine

5.50 (1,40)

0.024

Interaction

3.72 (1,40)

0.059

LSTR

Genotype

68.82 (1,40)

< 0.0001

Fluoxetine

6.24 (1,40)

0.017

Interaction

2.34 (1,40)

0.13

  1. Significant effects are highlighted in bold type.
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