Table 1 Physicochemical nanoparticle characterization.

From: Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease

Formulation

HD (nm)

PDI

ζ-potential (mV)

Unloaded ALNP

340

0.4

− 27

ALNP + DA

353

0.5

− 37

ALNP + AlClPc

497

0.6

− 29

  1. Physicochemical parameters observed in the different sub-variations of albumin/PLGA nanosystems tested, as determined by dynamic light scattering.
  2. Values were determined as the mean of three runs (10 measurements/run).
  3. ALNP albumin/PLGA nanosystems, AlClPc aluminum chloride phthalocyanine, DA dopamine, HD hydrodynamic diameter, PDI polydispersity index, ζ-potential zeta potential.
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