Figure 6 | Scientific Reports

Figure 6

From: Elevated S-adenosylhomocysteine induces adipocyte dysfunction to promote alcohol-associated liver steatosis

Figure 6

DZA downregulates protective adipokine secretion. Representative immunofluorescence image of (A) adiponectin in BODIPY 493/503 and DAPI stained control and DZA-treated 3T3-L1 adipocytes (Scale bar—20 µm). (B) Fluorescence intensity of adiponectin in representative DZA-treated cells normalized to % of control cells, n = 4 experiments; images of 32 random cells from each treatment group per experiment were captured using confocal microscope. (C) Adiponectin and (D) leptin levels in the culture medium of control and DZA-treated 3T3-L1 adipocytes normalized to cellular DNA and expressed as µg/µg DNA, n = 6. Data are presented as the mean ± SEM; values not sharing a common letter significantly differ from each other at p ≤ 0.05.

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