Table 2 Clinical comparison between non-metabolic and MetS subjects with normal and elevated APRI score in the study population.

n (M:F)

587 (283:304)

98 (53:45)

406 (216:200)

134 (71:63)

–

Weight (kg)

73.43 ± 0.70

78.93 ± 2.44

84.04 ± 0.81^a

87.21 ± 2.01

 < 0.05

Waist circumference (cm)

91.99 ± 0.61

95.24 ± 1.68

106.66 ± 0.61^a,b

106.54 ± 1.32^a

 < 0.01

BMI (kg/m²)

25.62 ± 0.39

26.95 ± 1.23

30.62 ± 0.31

30.59 ± 1.43

NS

Sistolic blood pressure (mmHg)

120.94 ± 0.74

124.71 ± 2.09

134.61 ± 0.90^a

134.41 ± 1.51^a

 < 0.05

Diastolic blood pressure (mmHg)

76.15 ± 0.32

76.13 ± 1.10

80.77 ± 0.31

81.55 ± 1.04

NS

Platelet count (10⁶/μL)

245.11 ± 2.76

172.74 ± 4.99^a,c

243.31 ± 2.31

179.94 ± 4.93^a,c

 < 0.05

Hemoglobin (g/dl)

13.91 ± 0.12

14.10 ± 0.31

13.81 ± 1.31

14.10 ± 0.13

NS

WBC (103/µl)

6.03 ± 0.08

5.60 ± 0.28

7.04 ± 1.83

6.30 ± 0.16

NS

Monocytes (%)

6.24 ± 0.07

6.81 ± 0.34

6.21 ± 0.04

6.78 ± 0.19

NS

Lymphocytes (%)

33.01 ± 0.38

32.89 ± 1

30.37 ± 0.38

32.98 ± 0.94

NS

Neutrophils (%)

57.51 ± 0.31

56.54 ± 1.21

59.42 ± 0.29

57.07 ± 0.94

NS

Basophils (%)

0.53 ± 0.03

0.6 ± 0.04

0.53 ± 0.02

0.56 ± 0.03

NS

Eosinophils (%)

2.73 ± 0.11

2.82 ± 0.32

2.71 ± 0.99

2.78 ± 0.21

NS

Glucose (mg/dl)

88.27 ± 0.81

92.30 ± 2.89

116 ± 2.82^a,b

120.61 ± 3.94^a,b

 < 0.05

HbA1c (mmol/mol)

37.47 ± 0.30

37.89 ± 1.51

47.82 ± 0.94^a,b

46.83 ± 1.41^a,b

 < 0.05

Total cholesterol (mg/dl)

189.04 ± 1.09

174.38 ± 4.31

175.12 ± 1.40

181.15 ± 3.99

NS

HDL-c (mg/dl)

60.65 ± 0.51

54.69 ± 2.31

47.01 ± 0.71^a,b

44.44 ± 1.32^a,b

 < 0.01

LDL-c (mg/dl)

110.42 ± 1.21

99.5 ± 4.40

99.31 ± 1.14

99.32 ± 3.42

NS

TG (mg/dl)

91.54 ± 1.32

95.64 ± 3.84

158.13 ± 4.31^a,b

165 ± 7.99^a,b

 < 0.05

AST (U/I)

20.06 ± 0.21

34.73 ± 1.03^a

20.54 ± 0.31

41.88 ± 1.52^a,c

 < 0.01

ALT (U/I)

26.35 ± 0.37

43.86 ± 2.96^a,c

29.79 ± 1.02

58.34 ± 3.25^a,c

 < 0.05

ALP (U/I)

66.47 ± 1.42

75.19 ± 2.98

72.12 ± 1.42

73.36 ± 2.52

NS

GGT (U/I)

27.11 ± 0.88

47 ± 4.93^a

37.32 ± 1.32

62.17 ± 5.31^a,c

 < 0.01

Ferritin (ng/ml)

96.32 ± 3.98

159.29 ± 13.99^a,c

114.32 ± 9.48^a

180.73 ± 18.33^a,c

 < 0.05

Iron (µg/dl)

84.21 ± 2.50

93.98 ± 7.12

86.32 ± 3.29

75.53 ± 4.23b

NS

Creatinine (mg/dl)

0.80 ± 1.49

0.86 ± 0.02

0.91 ± 1.99

0.87 ± 2.01

NS

Uric acid (mg/dl)

53.83 ± 0.18

57.99 ± 0.40

58.02 ± 0.31

60.33 ± 0.91^a

NS

Total protein (g/dl)

7.24 ± 1.40

7.22 ± 4.81

7.30 ± 4.32

7.41 ± 5.01

NS

Albumin (g/dl)

4.63 ± 0.84

4.43 ± 2.85

5.13 ± 0.59

4.37 ± 0.15

NS

ESR (mm/h)

14.02 ± 0.48

14.24 ± 1.73

21.32 ± 1.11^a,b

18.91 ± 1.94

NS

Hs-CRP (mg/l)

3.68 ± 0.17

3.76 ± 0.32

4.93 ± 0.42

4.50 ± 0.36

NS

TSH (mUI/L)

1.84 ± 0.10

2.02 ± 0.17

2.09 ± 0.63

1.96 ± 0.23

NS

FT3 (pg/ml)

2.82 ± 1.83

2.82 ± 6.01

2.76 ± 2.96

2.80 ± 5.83

NS

FT4 (ng/dl)

1.01 ± 1.12

0.99 ± 0.84

1.06 ± 1.45

1.07 ± 2.99

NS

Ab anti TG (UI/ml)

42.73 ± 12.01

42.69 ± 27.31

96 ± 47.86

15.36 ± 2.44

NS

Ab anti TPO (UI/ml)

441.71 ± 160.54

38.83 ± 13.93

259.96 ± 214.93

19.10 ± 2.86

NS

Cardiovascular risk (Framingham)

9.93 ± 0.83

21.95 ± 1.54^a

24.51 ± 0.91^a

39.97 ± 2.01^a,b,c

 < 0.01

FIB-4 score

1.13 ± 0.14

1.58 ± 0.16

1.04 ± 0.03

2.05 ± 0.21^a,c

 < 0.05

APRI score

0.28 ± 0.06

0.67 ± 0.04^a,c

0.28 ± 0.02

0.84 ± 0.09^a,c

 < 0.01