Figure 1 | Scientific Reports

Figure 1

From: Quantitative description of the interactions among kinase cascades underlying long-term plasticity of Aplysia sensory neurons

Figure 1

Dynamic regulation of pRSK (A) and PKA catalytic subunits (PKAc) (B) by a brief (5 min) pulse of 50 μM 5-HT. A1, Representative confocal images of pRSK immunofluorescence in SNs at different times post-onset of 5-HT. A2, Summary data. The percent change was calculated as the change of pRSK level after 5-HT compared to time-matched control levels. pRSK increased immediately after 5-HT (n = 8), returned to basal level at 15 min (n = 9), followed by a delayed increase at about 45 min (n = 13), and then a return to basal level at 60 min (n = 8). B1, Representative confocal images of PKAc at different times post-onset of 5-HT. B2, Summary data. The percent change was calculated as the change of PKAc level after 5-HT compared to time-matched control levels. PKAc increased immediately after 5-HT (n = 10), returned to basal level at 15 min (n = 7), and remained at basal level at 45 min (n = 8). Data are represented as mean ± SEM. All scale bars are 40 μm. *p < 0.05.

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