Table 2 Summary of behavioral data.

From: Randomized clinical trial shows no substantial modulation of empathy-related neural activation by intranasal oxytocin in autism

 

Oxytocin

Placebo

p'

d

M

SD

M

SD

Ratings

Physical pain

PP

3.91

0.47

3.94

0.45

1.000

0.07

PN

1.25

0.33

1.11

0.16

0.406

− 0.54

Basic emotions

SAD

1.62

0.25

1.49

0.31

0.429

− 0.46

HAP

4.44

0.40

4.54

0.40

1.000

0.25

EN

2.77

0.21

2.82

0.22

1.000

0.23

Social pain

SP

4.04

0.42

3.99

0.34

1.000

− 0.13

SN

1.22

0.37

1.12

0.21

1.000

− 0.33

RTs (ms)

Physical pain

PP

765

254

737

267

1.000

− 0.11

PN

698

248

694

239

1.000

− 0.02

Basic emotions

SAD

873

305

774

264

0.492

− 0.35

HAP

737

244

697

272

1.000

− 0.16

EN

706

269

709

253

1.000

0.01

Social pain

SP

974

328

972

410

1.000

− 0.01

SN

892

280

774

305

0.726

− 0.40

  1. p-values derive from paired t-tests comparing mean ratings after oxytocin and placebo administration. Values in the p′-column represent p-values adjusted for multiple comparisons using the Holm-Bonferroni correction while keeping the significance level of p < 0.05 constant. p′-values of 1.000 denote upper bound estimates. Data derived from n = 25 patients for the physical pain experiment, n = 23 for the basic emotions experiment, and n = 21 for the social pain experiment.
  2. RT Reaction time, PP physical pain, PN physical neutral, SAD Sad, HAP Happy, EN emotional neutral, SP social pain, SN social neutral, M mean, SD standard deviation.