Figure 2 | Scientific Reports

Figure 2

From: Proteomics reveals disturbances in the immune response and energy metabolism of monocytes from patients with septic shock

Figure 2

Functional analysis of the sepsis monocyte proteome. Enriched Reactome pathways among the differentially expressed proteins in groups (a) Sepsis, compared to Control and; (b) Sepsis, compared to Recovery. The y-axis represents the − log10 of the p value for the association between the pathways and the set of proteins up (red bars) or down (blue bars)-regulated. Significance (dotted lines) was defined as p ≥ 0.05 (Benjamini and Hochberg); (c) A network of pathways selected from (a,b). Nodes represent proteins up (red) or down (blue)-regulated in the comparisons between Sepsis and Control (circles), Sepsis end Recovery (squares), or both comparisons (triangles).

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