Table 5 Maternal body mass index in pregnancy and hazard of mental disorders in offspring born 1975–1999.
Offspring mental disorder | Model 1 | Model 2 | ||
|---|---|---|---|---|
Hazard ratio | p | Hazard ratio | p | |
(95% confidence interval) | (95% confidence interval) | |||
Any mental disorder | ||||
Underweight | 0.83 (0.48–1.44) | 0.51 | 0.75 (0.43–1.30) | 0.30 |
Normal weight | Reference category | |||
Overweight | 1.04 (0.89–1.22) | 0.59 | 1.06 (0.90–1.24) | 0.50 |
Moderate obesity | 1.05 (0.79–1.39) | 0.75 | 1.05 (0.79–1.39) | 0.75 |
Severe obesity | 1.55 (1.05–2.28) | 0.03 | 1.60 (1.08–2.38) | 0.02 |
Substance use disorder | ||||
Underweight | 0.73 (0.27–1.98) | 0.54 | 0.61 (0.23–1.64) | 0.33 |
Normal weight | Reference category | |||
Overweight | 0.89 (0.68–1.18) | 0.43 | 0.92 (0.70–1.21) | 0.55 |
Moderate obesity | 0.94 (0.58–1.54) | 0.81 | 0.94 (0.57–1.54) | 0.81 |
Severe obesity | 1.80 (0.97–3.31) | 0.06 | 1.91 (1.03–3.57) | 0.04 |
Schizophrenia spectrum disorders | ||||
Underweight | 0.31 (0.04–2.22) | 0.24 | 0.29 (0.04–2.06) | 0.21 |
Normal weight | Reference category | |||
Overweight | 1.42 (1.04–1.93) | 0.03 | 1.47 (1.07–2.00) | 0.02 |
Moderate Obesity | 1.26 (0.72–2.20) | 0.42 | 1.34 (0.76–2.37) | 0.31 |
Severe Obesity | 2.46 (1.24–4.87) | 0.01 | 2.80 (1.40–5.63) | 0.004 |
Mood disorder | ||||
Underweight | 1.15 (0.54–2.44) | 0.72 | 1.06 (0.50–2.26) | 0.87 |
Normal weight | Reference category | |||
Overweight | 1.08 (0.84–1.39) | 0.55 | 1.07 (0.83–1.38) | 0.60 |
Moderate obesity | 1.10 (0.70–1.71) | 0.68 | 1.06 (0.67–1.66) | 0.81 |
Severe obesity | 1.52 (0.80–2.88) | 0.20 | 1.46 (0.76–2.80) | 0.25 |
Anxiety disorder | ||||
Underweight | 0.77 (0.19–3.14) | 0.72 | 0.66 (0.16–2.70) | 0.57 |
Normal weight | Reference category | |||
Overweight | 1.00 (0.67–1.50) | 0.99 | 1.03 (0.69–1.55) | 0.88 |
Moderate obesity | 0.58 (0.23–1.44) | 0.24 | 0.57 (0.23–1.43) | 0.23 |
Severe obesity | 0.69 (0.17–2.84) | 0.61 | 0.72 (0.17–2.99) | 0.65 |
Other behavioural disorder | ||||
Underweight | 0 (NA) | 0.97 | 0 (NA) | 0.98 |
Normal weight | Reference category | |||
Overweight | 1.24 (0.65–2.36) | 0.51 | 1.24 (0.65–2.39) | 0.51 |
Moderate obesity | 0.35 (0.05–2.55) | 0.30 | 0.36 (0.05–2.68) | 0.32 |
Severe obesity | 1.03 (0.14–7.65) | 0.97 | 1.10 (0.15–8.30) | 0.93 |
Personality disorder | ||||
Underweight | 0 (NA) | 0.95 | 0 (NA) | 0.95 |
Normal weight | Reference category | |||
Overweight | 0.96 (0.58–1.57) | 0.86 | 1.01 (0.61–1.66) | 0.98 |
Moderate obesity | 1.77 (0.92–3.43) | 0.09 | 1.76 (0.90–3.44) | 0.10 |
Severe obesity | 0.97 (0.23–4.01) | 0.97 | 1.03 (0.24–4.31) | 0.97 |
Intellectual disability | ||||
Underweight | 2.13 (0.28–16.19) | 0.47 | 1.88 (0.25–14.44) | 0.54 |
Normal weight | Reference category | |||
Overweight | 2.49 (1.16–5.31) | 0.02 | 2.43 (1.13–5.23) | 0.02 |
Moderate obesity | 1.66 (0.38–7.33) | 0.50 | 1.52 (0.34–6.81) | 0.59 |
Severe obesity | 0 (NA) | 0.98 | 0 (NA) | 0.98 |
Suicide | ||||
Underweight | 0 (NA) | 0.96 | 0 (NA) | 0.96 |
Normal weight | Reference category | |||
Overweight | 1.06 (0.57–1.96) | 0.85 | 1.15 (0.62–2.13) | 0.67 |
Moderate obesity | 0.27 (0.04–1.97) | 0.19 | 0.32 (0.04–2.35) | 0.26 |
Severe obesity | 0.79 (0.11–5.86) | 0.82 | 1.01 (0.14–7.59) | 0.99 |
