Scientific Reports

Table 2 Univariate analyses: tSUVmax ≤ 7.2 versus tSUVmax > 7.2.

From: FDG-PET predicts bone invasion and prognosis in patients with oral squamous cell carcinoma

	Primary tumor SUVmax				Total (n = 340)		p value
	SUVmax ≤ 7.2		SUVmax > 7.2		Total (n = 340)
	N	%	N	%	N	%
Gender
Female	2	1.8	10	4.4	12	3.5	0.2155
Male	111	98.2	217	95.6	328	96.5
Age at diagnosis
< 60	70	61.9	134	59	204	60	0.6057
> 60	43	38.1	93	41	136	40
Site of tumors
Gingiva	53	46.9	150	66.1	203	59.7	0.0008
Hard palate	18	15.9	18	7.9	36	10.6
Floor of mouth	24	21.2	22	9.7	46	13.5
RMT	18	15.9	37	16.3	55	16.2
Pathological T stage
1	73	64.6	20	8.8	93	27.4	< 0.0001
2	19	16.8	35	15.4	54	15.9
3	2	1.8	7	3.1	9	2.6
4	19	16.8	165	72.7	184	54.1
Pathological N stage
0	65	78.3	143	72.2	208	74	0.7009
1	4	4.8	16	8.1	20	7.1
2	13	15.7	36	18.2	49	17.4
3	1	1.2	3	1.5	4	1.4
W/O ND	59
Stage
Early	79	69.9	45	19.8	124	36.5	< 0.0001
Advance	34	30.1	182	80.2	216	63.5
Depth of tumor invasion
DOI ≤ 15 mm	110	97.3	175	77.1	285	83.8	< 0.0001
DOI > 15 mm	3	2.7	52	22.9	55	16.2
Bone invasion
No	96	85	64	28.2	160	47.1	< 0.0001
Yes	17	15	163	71.8	180	52.9
Extranodal spread
No	70	87.5	171	85.1	241	85.8	0.6002
Yes	10	12.5	30	14.9	40	14.2
W/O ND	59
Perineural invasion
No	97	85.8	145	63.9	242	71.2	< 0.0001
Yes	16	14.2	82	36.1	98	28.8
Lymphovascular invasion
No	92	81.4	143	63	235	69.1	0.0005
Yes	21	18.6	84	37	105	30.9
Positive margin involved
No	109	96.5	217	95.6	326	95.9	0.7056
Yes	4	3.5	10	4.4	14	4.1
Grade
Well	11	9.7	24	10.6	35	10.3	0.9604
Moderately	95	84.1	190	83.7	285	83.8
Poor	7	6.2	13	5.7	20	5.9

p value by Chi-squared test.
W/O ND without neck dissection, RMT retromolar trigone, Early stage AJCC stage I and II, Advanced stage stage III and IV.

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