Figure 3 | Scientific Reports

Figure 3

From: A bioimpedance-based monitor for real-time detection and identification of secondary brain injury

Figure 3The alternative text for this image may have been generated using AI.

Computed tomography imaging integration and precise capture of evolving intracranial injury. (a) Axial, sagittal and coronal views of cross-sectional masks of the brain created in Mimics. Images spatially advance left to right. (b) 3D segmentation of the same brain generated from interpolation between masks. (c) Segmented intracranial brain volumes for all pigs. (d) oronal view of inflating Fogarty balloon from 0 to 1.2 mL volume. (e) Coronal view of injected autologous blood from 0 to 1.2 mL volume. (f) Stealth navigation surgical plan used for precise placement of the three intracranial instruments, enabled through registration with pre-operative images. (g) 3D reconstruction of post-op intracranial space with three catheters in place and segmented for localization. (h) ICP response summaries across pigs (n = 9) for each protocol phase. Error bars represent  ± one standard deviation. Note the ICP increases as volume increases for balloon inflation and blood injection.

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