Figure 2 | Scientific Reports

Figure 2

From: Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides

Figure 2

Changes to predicted exon splicing enhancer/silencer (ESE/ESS) access in five examples of antisense oligonucleotide (AO)-induced cryptic splicing of canonical exons. Blue lines indicate ESE access and red lines indicate ESS access. Grey shading indicates pre-mRNA sequence excluded from the mature transcript. Region sizes and Maximum Entropy scores for cryptic and canonical splice sites are also shown.

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