Table 2 Exonic splicing enhancer motifs masked by the antisense oligonucleotides examined in this study.
From: Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides
Gene | AO nomenclature | SRSF1 (SF2) | SRSF2 (SC35) | SRSF5 (SRp40) | SRSF6 (SRp55) |
|---|---|---|---|---|---|
USH2A | H13A(−05+20) | 1 | 1 | 1 | 0 |
H13A(+70+94) | 1 | 4 | 0 | 0 | |
H13A(+136+160) | 1 | 1 | 2 | 0 | |
H13A(+161+183) | 2 | 2 | 1 | 1 | |
COL7A1 | H15A(+91+115) | 3 | 2 | 1 | 1 |
H15D(+14–11) | 2 | 2 | 0 | 1 | |
ATXN3 | H9A(+38+62) | 3 | 0 | 2 | 1 |
H9D(+20–05) | 1 | 0 | 2 | 0 | |
SRSF2 | H2A(+268+292) | 4 | 2 | 1 | 0 |
H2D(+10–12) | 0 | 1 | 1 | 0 | |
HTT | H12A(+269+297)a | 3 | 4 | 3 | 0 |
LMNA | H11A(+221+245)a | 3 | 3 | 1 | 1 |