Table 3 Novel CMR parameters.

From: CMR-based T1-mapping offers superior diagnostic value compared to longitudinal strain-based assessment of relative apical sparing in cardiac amyloidosis

 

CA N = 30

HCM N = 20

Control N = 15

p-value CA vs. HCM

p-value CA vs. Control

p-value HCM vs. Control

T1-mappping

Native T1-mapping global, ms

1119 (1095–1174)

1014 (991–1051)

983 (964–993)

< 0.001

< 0.001

0.30

Native T1-mapping basal, ms

1146 (± 68)

1024 (± 40)

985 (± 16)

< 0.001

< 0.001

0.005

Native T1-mapping mid, ms

1115 (1078–1171)

1021 (987–1057)

976 (965–991)

< 0.001

< 0.001

0.13

Native T1-mapping apical, ms

1141 (1074–1192)

994 (979–1045)

994 (962–1004)

< 0.001

< 0.001

1.0

ECV

ECV global, %

50 (± 9)

28 (± 10)

28 (± 3)

< 0.001

< 0.001

1.0

ECV basal, %

53 (± 10)

28 (± 5)

27 (± 3)

< 0.001

< 0.001

0.64

ECV mid, %

49 (± 8)

28 (± 7)

27 (± 2)

< 0.001

< 0.001

1.0

ECV apical, %

50 (± 9)

29 (± 6)

29 (± 4)

< 0.001

< 0.001

0.99

FT-strain parameters

Longitudinal systolic peak strain (3D) global, %

− 6.7 (− 8.7 to − 4.9)

− 10.5 (− 11.4 to − 8.1)

− 13.6 (− 14.9 to − 11.7)

0.025

< 0.001

0.025

Longitudinal systolic peak strain (3D) basal, %

− 5.7 (− 6.8 to − 3.6)

− 8.3 (− 12.1 to − 5.3)

− 12.9 (− 15.4 to − 10.9)

0.036

< 0.001

0.07

Longitudinal systolic peak strain (3D) mid, %

− 5.2 (− 6.9 to − 3.4)

− 8.9 (− 11 to − 6.8)

− 12.5 (− 14 to − 10)

0.003

< 0.001

0.07

Longitudinal systolic peak strain (3D) apical, %

− 10.4 (± 3.1)

− 12.9 (± 3.6)

− 16.4 (± 2.4)

0.026

< 0.001

0.005

Apical/(basal + mid) strain ratio (3D), n

0.96 (0.82–1.18)

0.72 (0.63–0.88)

0.65 (0.60–0.74)

0.004

0.001

0.74

  1. Bold values indicate significant p-value < 0.05.
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