Table 1 Performance values of AnnoMiner compared to other TF enrichment web-tools.
Tool | Method | ROC AUC | PR AUC | % recovered | AD-test | # of datasets |
|---|---|---|---|---|---|---|
ChEA3 | meanRank | 0.83 | 0.81 | 6.7 | 8.00E−06 | 75 |
topRank | 0.82 | 0.81 | 9.3 | 8.00E−06 | ||
AnnoMiner |  | 0.63 | 0.63 | 4.0 | 8.10E−05 | |
TFEA.ChIP |  | 0.63 | 0.60 | 0.0 | 7.90E−04 | 57 |
AnnoMiner |  | 0.67 | 0.67 | 5.3 | 1.07E−05 | |
EnrichR | TRRUST_Transcription_Factors_2019 | 0.71 | 0.72 | 7.8 | 1.18E−05 | 51 |
AnnoMiner |  | 0.63 | 0.65 | 5.9 | 5.57E−04 | |
EnrichR | ENCODE_TF_ChIP-seq_2015 | 0.68 | 0.68 | 4.6 | 3.59E−05 | 44 |
AnnoMiner |  | 0.72 | 0.71 | 6.8 | 1.36E−05 | |
EnrichR | ChEA_2016 | 0.70 | 0.72 | 18.2 | 1.36E−05 | 44 |
AnnoMiner |  | 0.67 | 0.68 | 4.6 | 5.12E−05 | |
EnrichR | ARCHS4_TFs_Coexp | 0.65 | 0.67 | 6.8 | 8.11E−06 | 74 |
AnnoMiner |  | 0.63 | 0.64 | 4.1 | 6.05E−05 | |
EnrichR | ENCODE_and_ChEA_Consensus | 0.57 | 0.60 | 10.3 | 0.27 | 29 |
AnnoMiner |  | 0.76 | 0.75 | 6.9 | 2.07E−05 |
