Table 3 Diagnostic performance of ADCmean, ADCmin and radiomics model in training set and test set.
Single parameter | Radiomics model | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADCmean | ADCmin | MLR-R | RF-R | MLR-I | RF-I | MLR-E | RF-E | MLR-A | RF-A | |||
Train set | R1 | AUC | 0.712 | 0.759 | 0.848 | 0.807 | 0.883 | 0.846 | 0.876 | 0.841 | 0.883 | 0.860 |
Sensitivity (%) | 68.1 | 70.2 | 78.7 | 66.0 | 78.7 | 68.1 | 74.5 | 74.5 | 78.7 | 68.1 | ||
Specificity (%) | 81.0 | 81.0 | 77.6 | 79.3 | 84.5 | 84.5 | 86.2 | 82.8 | 84.5 | 86.2 | ||
Accuracy (%) | 70.5 | 74.3 | 78.1 | 73.3 | 81.9 | 77.1 | 81.0 | 79.0 | 81.9 | 78.1 | ||
R2 | AUC | 0.697 | 0.719 | 0.848 | 0.807 | 0.873 | 0.820 | 0.875 | 0.834 | 0.875 | 0.841 | |
Sensitivity (%) | 68.1 | 68.1 | 78.7 | 66.0 | 78.7 | 70.2 | 72.3 | 72.3 | 72.3 | 68.1 | ||
Specificity (%) | 70.7 | 79.3 | 77.6 | 79.3 | 82.8 | 79.3 | 87.8 | 81.0 | 82.8 | 82.8 | ||
Accuracy (%) | 69.5 | 74.3 | 78.1 | 73.3 | 81.0 | 75.2 | 78.1 | 77.1 | 78.1 | 76.2 | ||
Test set | R1 | AUC | 0.729 | 0.753 | 0.698 | 0.700 | 0.773 | 0.807 | 0.762 | 0.744 | 0.773 | 0.807 |
p value† | 0.551 | 0.745 | 0.782 | 0.456 | 0.259 | 0.537 | 0.827 | 0.456 | 0.259 | |||
p value‡ | 0.551 | 0.559 | 0.599 | 0.653 | 0.408 | 0.861 | 0.907 | 0.653 | 0.408 | |||
Sensitivity (%) | 66.7 | 70.8 | 58.3 | 75.0 | 75.0 | 83.3 | 70.8 | 70.8 | 75.0 | 83.3 | ||
Specificity (%) | 81.8 | 86.4 | 68.2 | 63.6 | 63.6 | 59.1 | 54.5 | 59.1 | 63.6 | 59.1 | ||
Accuracy (%) | 73.9 | 78.3 | 63.0 | 69.6 | 69.6 | 71.1 | 63.0 | 65.2 | 69.6 | 71.1 | ||
R2 | AUC | 0.689 | 0.711 | 0.698 | 0.700 | 0.727 | 0.771 | 0.742 | 0.775 | 0.742 | 0.775 | |
p value† | 0.562 | 0.932 | 0.922 | 0.664 | 0.306 | 0.312 | 0.330 | 0.312 | 0.330 | |||
p value‡ | 0.562 | 0.895 | 0.915 | 0.841 | 0.430 | 0.561 | 0.476 | 0.561 | 0.476 | |||
Sensitivity (%) | 54.2 | 62.5 | 58.3 | 75.0 | 70.8 | 66.7 | 75.0 | 70.8 | 75.0 | 70.8 | ||
Specificity (%) | 90.9 | 90.9 | 68.2 | 63.6 | 63.6 | 59.1 | 54.5 | 59.1 | 54.5 | 59.1 | ||
Accuracy (%) | 71.7 | 76.1 | 63.0 | 69.6 | 67.4 | 63.0 | 65.2 | 65.2 | 65.2 | 65.2 | ||
