Table 1 Association rules found using itemset mining. Support, confidence and lift are given to 2 significant figures.

Group	Antecedent	Consequent	Support	Confidence	Lift
1	Significant skewness & strongly sub-diffusive MSD exponent	No sustained curvature	0.41	0.93	1.1
	Perinuclear & strongly sub-diffusive MSD exponent	No sustained curvature	0.24	1.0	1.1
	Significant skewness & perinuclear & strongly sub-diffusive MSD exponent	No sustained curvature	0.18	1.0	1.1
2	Thermalised or active MSD exponent & significant skewness	Perinuclear	0.32	0.92	1.6
2	Thermalised or active MSD exponent & perinuclear	Significant skewness	0.32	0.92	1.2
3	Peripheral & strongly sub-diffusive MSD exponent	No sustained curvature	0.29	0.91	1.0
	No significant skewness	No sustained curvature	0.21	1.0	1.1
	Peripheral & no significant skewness	No sustained curvature	0.12	1.0	1.1
4	Sustained curvature	Significant skewness	0.12	1.0	1.3
1 & 3	Strongly sub-diffusive MSD exponent	No sustained curvature	0.53	0.95	1.1

Support gives the proportion of tubules in which a given itemset occurs and confidence is a measure of how often a rule applies within the population of tubules for which the antecedent is true. Lift is a measure of how much more likely the consequent is to occur along with the antecedent than on its own, considering all tubules (see “Methods”). Rules which are related are grouped together. The last row relates to both groups 1 and 3.

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